Edinburgh CRF



Publications

AuthorsTitlePublicationPublication DateVolumeIssuePages
Alonso N, Estrada K, Albagha OME, Herrera L, Reppe S, Olstad OK, et al.
Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density.Annals of the rheumatic diseases
3/2018
77
3
378-385
Han X, Nieman MT
PAR4 (Protease-Activated Receptor 4): PARticularly Important 4 Antiplatelet Therapy.Arteriosclerosis, thrombosis, and vascular biology
2/2018
38
2
287-289
Marioni RE, Harris SE, Shah S, McRae AF, von Zglinicki T, Martin-Ruiz C, et al.
The epigenetic clock and telomere length are independently associated with chronological age and mortality.International journal of epidemiology
2/2018
47
1
356
Navrady LB, Wolters MK, MacIntyre DJ, Clarke TK, Campbell AI, Murray AD, et al.
Cohort Profile: Stratifying Resilience and Depression Longitudinally (STRADL): a questionnaire follow-up of Generation Scotland: Scottish Family Health Study (GS:SFHS).International journal of epidemiology
2/2018
47
1
13-14g
Wilson SJ, Ismat FA, Wang Z, Cerra M, Narayan H, Raftis J, et al.
PAR4 (Protease-Activated Receptor 4) Antagonism With BMS-986120 Inhibits Human Ex Vivo Thrombus Formation.Arteriosclerosis, thrombosis, and vascular biology
2/2018
38
2
448-456
Allardyce J, Leonenko G, Hamshere M, Pardiñas AF, Forty L, Knott S, et al.
Association Between Schizophrenia-Related Polygenic Liability and the Occurrence and Level of Mood-Incongruent Psychotic Symptoms in Bipolar Disorder.JAMA psychiatry
1/2018
75
1
28-35
Gilbert E, O'Reilly S, Merrigan M, McGettigan D, Molloy AM, Brody LC, et al.
The Irish DNA Atlas: Revealing Fine-Scale Population Structure and History within Ireland.Scientific reports
12/2017
7
1
17199
Harris SE, Riggio V, Evenden L, Gilchrist T, McCafferty S, Murphy L, et al.
Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936.Aging
12/2017
9
12
2489-2503
Karlsson Linnér R, Marioni RE, Rietveld CA, Simpkin AJ, Davies NM, Watanabe K, et al.
An epigenome-wide association study meta-analysis of educational attainment.Molecular psychiatry
12/2017
22
12
1680-1690
Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, et al.
Exome-wide association study of plasma lipids in >300,000 individuals.Nature genetics
12/2017
49
12
1758-1766
Richard MA, Huan T, Ligthart S, Gondalia R, Jhun MA, Brody JA, et al.
DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation.American journal of human genetics
12/2017
101
6
888-902
Feig DS, Donovan LE, Corcoy R, Murphy KE, Amiel SA, Hunt KF, et al.
Continuous glucose monitoring in pregnant women with type 1 diabetes (CONCEPTT): a multicentre international randomised controlled trial.Lancet (London, England)
11/2017
390
10110
2347-2359
Howard DM, Hall LS, Hafferty JD, Zeng Y, Adams MJ, Clarke TK, et al.
Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank.Translational psychiatry
11/2017
7
11
1263
Lam M, Trampush JW, Yu J, Knowles E, Davies G, Liewald DC, et al.
Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.Cell reports
11/2017
21
9
2597-2613
Navrady LB, Adams MJ, Chan SWY, , Ritchie SJ, McIntosh AM
Genetic risk of major depressive disorder: the moderating and mediating effects of neuroticism and psychological resilience on clinical and self-reported depression.Psychological medicine
11/2017


1-10
Trampush JW, Yang MLZ, Yu J, Knowles E, Davies G, Liewald DC, et al.
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium.Molecular psychiatry
11/2017
22
11
1651-1652
Zhang E, Bell AJ, Wilkie GS, Suárez NM, Batini C, Veal CD, et al.
Inherited Chromosomally Integrated Human Herpesvirus 6 Genomes Are Ancient, Intact, and Potentially Able To Reactivate from Telomeres.Journal of virology
11/2017
91
22

Joshi PK, Pirastu N, Kentistou KA, Fischer K, Hofer E, Schraut KE, et al.
Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity.Nature communications
10/2017
8
1
910
Kraja AT, Cook JP, Warren HR, Surendran P, Liu C, Evangelou E, et al.
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals.Circulation. Cardiovascular genetics
10/2017
10
5

Neilson E, Bois C, Clarke TK, Hall L, Johnstone EC, Owens DGC, et al.
Polygenic risk for schizophrenia, transition and cortical gyrification: a high-risk study.Psychological medicine
10/2017


1-11
Smeland OB, Frei O, Kauppi K, Hill WD, Li W, Wang Y, et al.
Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function.JAMA psychiatry
10/2017
74
10
1065-1075
Schubert SA, Ruano D, Elsayed FA, Boot A, Crobach S, Sarasqueta AF, et al.
Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia.British journal of cancer
9/2017
117
6
1215-1223
Wheeler E, Leong A, Liu CT, Hivert MF, Strawbridge RJ, Podmore C, et al.
Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.PLoS medicine
9/2017
14
9
e1002383
Li S, Christiansen L, Christensen K, Kruse TA, Redmond P, Marioni RE, et al.
Identification, replication and characterization of epigenetic remodelling in the aging genome: a cross population analysis.Scientific reports
8/2017
7
1
8183
Singh T, Walters JTR, Johnstone M, Curtis D, Suvisaari J, Torniainen M, et al.
The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability.Nature genetics
8/2017
49
8
1167-1173
Wigmore EM, Clarke TK, Howard DM, Adams MJ, Hall LS, Zeng Y, et al.
Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n=19 762), UK Biobank (n=24 048) and the English Longitudinal Study of Ageing (n=5766).Translational psychiatry
8/2017
7
8
e1205
Wain LV, Vaez A, Jansen R, Joehanes R, van der Most PJ, Erzurumluoglu AM, et al.
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.Hypertension (Dallas, Tex. : 1979)
7/2017



Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, et al.
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.Nature communications
7/2017
8
1
80
Christophersen IE, Rienstra M, Roselli C, Yin X, Geelhoed B, Barnard J, et al.
Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.Nature genetics
6/2017
49
6
946-952
Cox SR, Ritchie SJ, Dickie DA, Pattie A, Royle NA, Corley J, et al.
Interaction of APOE e4 and poor glycemic control predicts white matter hyperintensity growth from 73 to 76.Neurobiology of aging
6/2017
54

54-58
Day FR, Thompson DJ, Helgason H, Chasman DI, Finucane H, Sulem P, et al.
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.Nature genetics
6/2017
49
6
834-841
Hagenaars SP, Gale CR, Deary IJ, Harris SE
Cognitive ability and physical health: a Mendelian randomization study.Scientific reports
6/2017
7
1
2651
Petrie JR et al.
Cardiovascular and metabolic effects of metformin in patients with type 1 diabetes (REMOVAL): a double-blind, randomised, placebo-controlled trialThe Lancet Diabetes & Endocrinology
6/2017



Sharp GC, Ho K, Davies A, Stergiakouli E, Humphries K, McArdle W, Sandy J, Davey Smith G, Lewis SJ, Relton CL
Distinct DNA methylation profiles in subtypes of orofacial cleftClinical epigenetics
6/2017
9
63

Teng S, Thomson PA, McCarthy S, Kramer M, Muller S, Lihm J, et al.
Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia.Molecular psychiatry
6/2017



Xue Y, Mezzavilla M, Haber M, McCarthy S, Chen Y, Narasimhan V, et al.
Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations.Nature communications
6/2017
8

15927
Bowman L, Chen F, Sammons E, Hopewell JC, Wallendszus K, Stevens W, Valdes-Marquez E, Wiviott S, Cannon CP, Braunwald E, Collins R and Landray MJ
Randomized Evaluation of the Effects of Anacetrapib through Lipid-modification (REVEAL)—A large-scale, randomized, placebo-controlled trial of the clinical effects of anacetrapib among people with established vascular disease: Trial design, recruitment, and baseline characteristicsAmerican Heart Journal
5/2017
187

182–190
Lubitz SA, Parsons OE, Anderson CD, Benjamin EJ, Malik R, Weng LC, et al.
Atrial Fibrillation Genetic Risk and Ischemic Stroke Mechanisms.Stroke
5/2017



Mak E, Gabel S, Mirette H, Su L, Williams GB, Waldman A, et al.
Structural neuroimaging in preclinical dementia: From microstructural deficits and grey matter atrophy to macroscale connectomic changes.Ageing research reviews
5/2017
35

250-264
Russ TC, Hannah J, Batty GD, Booth CC, Deary IJ, Starr JM
Childhood Cognitive Ability and Incident Dementia: The 1932 Scottish Mental Survey Cohort into their 10th Decade.Epidemiology (Cambridge, Mass.)
5/2017
28
3
361-364
Bethel MA, Engel SS, Green JB, Huang Z, Josse RG, Kaufman KD, et al.
Assessing the Safety of Sitagliptin in Older Participants in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS).Diabetes care
4/2017
40
4
494-501
Brook RD, Anderson JA, Calverley PM, Celli BR, Crim C, Denvir MA, et al.
Cardiovascular outcomes with an inhaled beta2-agonist/corticosteroid in patients with COPD at high cardiovascular risk.Heart (British Cardiac Society)
4/2017



Clarke TK, Obsteter J, Hall LS, Hayward C, Thomson PA, Smith BH, et al.
Investigating shared aetiology between type 2 diabetes and major depressive disorder in a population based cohort.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
4/2017
174
3
227-234
Cox SR, Valdés Hernández MD, Kim J, Royle NA, MacPherson SE, Ferguson KJ, et al.
Associations between hippocampal morphology, diffusion characteristics, and salivary cortisol in older men.Psychoneuroendocrinology
4/2017
78

151-158
Graff M et al.
Genome-wide physical activity interactions in adiposity ― a meta-analysis of 200,452 adultsPLOS Genetics
4/2017



Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, et al.
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.PLoS genetics
4/2017
13
4
e1006528
Hägg S, Zhan Y, Karlsson R, Gerritsen L, Ploner A, van der Lee SJ, et al.
Short telomere length is associated with impaired cognitive performance in European ancestry cohorts.Translational psychiatry
4/2017
7
4
e1100
Hunter AL, Shah AS, Langrish JP, Raftis JB, Lucking AJ, Brittan M, et al.
Fire Simulation and Cardiovascular Health in Firefighters.Circulation
4/2017
135
14
1284-1295
Jenkins WS, Vesey AT, Stirrat C, Connell M, Lucatelli C, Neale A, et al.
Cardiac αVβ3 integrin expression following acute myocardial infarction in humans.Heart (British Cardiac Society)
4/2017
103
8
607-615
Justice AE, Winkler TW, Feitosa MF, Graff M, Fisher VA, Young K, et al.
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.Nature communications
4/2017
8

14977
Maguire J et al.
GISCOME – Genetics of Ischaemic Stroke Functional Outcome network: A protocol for an international multicentre genetic association studyEuropean Stroke Journal
4/2017



Miller MR, Raftis JB, Langrish JP, McLean SG, Samutrtai P, Connell SP, et al.
Inhaled Nanoparticles Accumulate at Sites of Vascular Disease.ACS nano
4/2017



Valdés Hernández MD, Cox SR, Kim J, Royle NA, Muñoz Maniega S, Gow AJ, et al.
Hippocampal morphology and cognitive functions in community-dwelling older people: the Lothian Birth Cohort 1936.Neurobiology of aging
4/2017
52

1-11
Black HA, Leighton DJ, Cleary EM, Rose E, Stephenson L, Colville S, et al.
Genetic epidemiology of motor neuron disease-associated variants in the Scottish population.Neurobiology of aging
3/2017
51

178.e11-178.e20
Datta D, Grahamslaw J, Gray AJ, Graham C
Capillary and Venous Lactate Agreement: a pilot prospective observational study. Emergency Medicine Journal
3/2017
34
3
195-197
Gale CR, Ritchie SJ, Cooper C, Starr JM, Deary IJ
Cognitive Ability in Late Life and Onset of Physical Frailty: The Lothian Birth Cohort 1936.Journal of the American Geriatrics Society
3/2017



Habib M, Mak E, Gabel S, Su L, Williams G, Waldman A, et al.
FUNCTIONAL NEUROIMAGING FINDINGS IN HEALTHY MIDDLE-AGED ADULTS AT RISK OF ALZHEIMER's DISEASE.Ageing research reviews
3/2017



Harris MA, Cox SR, Brett CE, Deary IJ, MacLullich AM
Stress in childhood, adolescence and early adulthood, and cortisol levels in older age.Stress (Amsterdam, Netherlands)
3/2017
20
2
140-148
Huisman J
Pedigree reconstruction from SNP data: Parentage assignment, sibship clustering, and beyond.Molecular ecology resources
3/2017



Li M, Li Y, Weeks O, Mijatovic V, Teumer A, Huffman JE, et al.
SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function.Journal of the American Society of Nephrology : JASN
3/2017
28
3
981-994
Liddle J, Beaufils B, Binnie M, Bouillot A, Denis AA, Hann MM, et al.
The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis.Bioorganic & medicinal chemistry letters
3/2017



Malik R, Dau T, Gonik M, Sivakumar A, Deredge DJ, Edeleva EV, et al.
Common coding variant in SERPINA1 increases the risk for large artery stroke.Proceedings of the National Academy of Sciences of the United States of America
3/2017



McLaughlin RL, Schijven D, van Rheenen W, van Eijk KR, O'Brien M, Kahn RS, et al.
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia.Nature communications
3/2017
8

14774
Nagy R, Boutin TS, Marten J, Huffman JE, Kerr SM, Campbell A, et al.
Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.Genome medicine
3/2017
9
1
23
Ng KT, Alston RP, Just G, McKenzie C
Coronary Sinus Isoflurane Concentration in Cardiac Surgery.Journal of cardiothoracic and vascular anesthesia
3/2017



Ritchie K, Carrière I, Su L, O'Brien JT, Lovestone S, Wells K, et al.
The midlife cognitive profiles of adults at high risk of late-onset Alzheimer's disease: The PREVENT study.Alzheimer's & dementia : the journal of the Alzheimer's Association
3/2017



Souter C, Kinnear A, Kinnear M and Mead G
A pilot study to assess the practicality, acceptability and feasibility of a randomised controlled trial to evaluate the impact of a pharmacist complex intervention on patients with stroke in their own homesEuropean Journal of Hospital Pharmacy
3/2017
24
2

Taylor A M, Ritchie S J and Deary I J
Associations of intelligence across the life course with optimism and pessimism in older ageIntelligence
3/2017
62

79-88
Trampush JW, Yang ML, Yu J, Knowles E, Davies G, Liewald DC, et al.
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium.Molecular psychiatry
3/2017
22
3
336-345
Traylor M, Malik R, Nalls MA, Cotlarciuc I, Radmanesh F, Thorleifsson G, et al.
Genetic variation at 16q24.2 is associated with small vessel stroke.Annals of neurology
3/2017
81
3
383-394
Vesey AT, Jenkins WS, Irkle A, Moss A, Sng G, Forsythe RO, et al.
(18)F-Fluoride and (18)F-Fluorodeoxyglucose Positron Emission Tomography After Transient Ischemic Attack or Minor Ischemic Stroke: Case-Control Study.Circulation. Cardiovascular imaging
3/2017
10
3

Wain LV, Shrine N, Artigas MS, Erzurumluoglu AM, Noyvert B, Bossini-Castillo L, et al.
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.Nature genetics
3/2017
49
3
416-425
Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B, et al.
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.Nature genetics
3/2017
49
3
403-415
Webster SP, McBride A, Binnie M, Sooy K, Seckl JR, Andrew R, et al.
Selection and early clinical evaluation of the brain-penetrant 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor UE2343 (Xanamem™).British journal of pharmacology
3/2017
174
5
396-408
Weller RB
The health benefits of UV radiation exposure through vitamin D production or non-vitamin D pathways. Blood pressure and cardiovascular disease.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
3/2017
16
3
374-380
Williams MC, Mirsadraee S, Dweck MR, Weir NW, Fletcher A, Lucatelli C, et al.
Computed tomography myocardial perfusion vs (15)O-water positron emission tomography and fractional flow reserve.European radiology
3/2017
27
3
1114-1124
Buse JB, Bethel MA, Green JB, Stevens SR, Lokhnygina Y, Aschner P, et al.
Pancreatic Safety of Sitagliptin in the TECOS Study.Diabetes care
2/2017
40
2
164-170
Chappell FM, Del Carmen Valdés Hernández M, Makin SD, Shuler K, Sakka E, Dennis MS, et al.
Sample size considerations for trials using cerebral white matter hyperintensity progression as an intermediate outcome at 1 year after mild stroke: results of a prospective cohort study.Trials
2/2017
18
1
78
Davies R, Southwood T, Kearsley-Fleet L, Lunt M, Baildam E, Beresford MW, et al.
Mortality rates are increased in patients with systemic juvenile idiopathic arthritis.Archives of disease in childhood
2/2017
102
2
206-207
de Lange KM, Moutsianas L, Lee JC, Lamb CA, Luo Y, Kennedy NA, et al.
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.Nature genetics
2/2017
49
2
256-261
Ercan A, Kohrt WM, Cui J, Deane KD, Pezer M, Yu EW, et al.
Estrogens regulate glycosylation of IgG in women and men.JCI insight
2/2017
2
4
e89703
George JT, Hendrikse M, Veldhuis JD, Clarke IJ, Anderson RA, Millar RP
Effect of gonadotropin inhibitory hormone (GnIH) on luteinizing hormone secretion in humans.Clinical endocrinology
2/2017



Gilbert E, Carmi S, Ennis S, Wilson JF, Cavalleri GL
Genomic insights into the population structure and history of the Irish Travellers.Scientific reports
2/2017
7

42187
Hagenaars SP, Hill WD, Harris SE, Ritchie SJ, Davies G, Liewald DC, et al.
Genetic prediction of male pattern baldness.PLoS genetics
2/2017
13
2
e1006594
Hammersley VS, Harris J, Sheikh A, Davidson E, Walker S
Developing and testing of a screening tool to predict people without IgE-mediated allergy: a quantitative analysis of the predictive value of a screening tool.The British journal of general practice : the journal of the Royal College of General Practitioners
2/2017



Lee JC, Biasci D, Roberts R, Gearry RB, Mansfield JC, Ahmad T, et al.
Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease.Nature genetics
2/2017
49
2
262-268
Luo Y, de Lange KM, Jostins L, Moutsianas L, Randall J, Kennedy NA, et al.
Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7.Nature genetics
2/2017
49
2
186-192
Marouli E, Graff M, Medina-Gomez C, Lo KS, Wood AR, Kjaer TR, et al.
Rare and low-frequency coding variants alter human adult height.Nature
2/2017
542
7640
186-190
Mõttus R, Marioni R, Deary IJ
Markers of Psychological Differences and Social and Health Inequalities: Possible Genetic and Phenotypic Overlaps.Journal of personality
2/2017
85
1
104-117
Muñoz Maniega S, Chappell FM, Valdés Hernández MC, Armitage PA, Makin SD, Heye AK, et al.
Integrity of normal-appearing white matter: Influence of age, visible lesion burden and hypertension in patients with small-vessel disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
2/2017
37
2
644-656
Ritchie K, Ropacki M, Albala B, Harrison J, Kaye J, Kramer J, et al.
Recommended cognitive outcomes in preclinical Alzheimer's disease: Consensus statement from the European Prevention of Alzheimer's Dementia project.Alzheimer's & dementia : the journal of the Alzheimer's Association
2/2017
13
2
186-195
Snowdon VK, Lachlan NJ, Hoy AM, Hadoke PW, Semple SI, Patel D, et al.
Serelaxin as a potential treatment for renal dysfunction in cirrhosis: Preclinical evaluation and results of a randomized phase 2 trial.PLoS medicine
2/2017
14
2
e1002248
Stimson RH, Anderson AJ, Ramage LE, Macfarlane DP, de Beaux AC, Mole DJ, et al.
Acute physiological effects of glucocorticoids on fuel metabolism in humans are permissive but not direct.Diabetes, obesity & metabolism
2/2017



Williams MC, Hunter A, Shah A, Assi V, Lewis S, Mangion K, et al.
Symptoms and quality of life in patients with suspected angina undergoing CT coronary angiography: a randomised controlled trial.Heart (British Cardiac Society)
2/2017



Aschard H, Tobin MD, Hancock DB, Skurnik D, Sood A, James A, et al.
Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.International journal of epidemiology
1/2017



Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, et al.
The complex genetics of gait speed: genome-wide meta-analysis approach.Aging
1/2017
9
1
209-246
Corre T, Olinger E, Harris SE, Traglia M, Ulivi S, Lenarduzzi S, et al.
Common variants in CLDN14 are associated with differential excretion of magnesium over calcium in urine.Pflugers Archiv : European journal of physiology
1/2017
469
1
91-103
Creamer F, Balfour A, Nimmo S, Foo I, Norrie JD, Williams LJ, et al.
Randomized open-label phase II study comparing oxycodone-naloxone with oxycodone in early return of gastrointestinal function after laparoscopic colorectal surgery.The British journal of surgery
1/2017
104
1
42-51
de Las Heras JI, Zuleger N, Batrakou DG, Czapiewski R, Kerr AR, Schirmer EC
Tissue-specific NETs alter genome organization and regulation even in a heterologous system.Nucleus (Austin, Tex.)
1/2017
8
1
81-97
Greenhalgh KA, Strachan MW, Alzahrani S, Baxter PD, Standeven KF, Storey RF, et al.
BβArg448Lys polymorphism is associated with altered fibrin clot structure and fibrinolysis in type 2 diabetes.Thrombosis and haemostasis
1/2017
117
2
295-302
Hedman ÅK, Mendelson MM, Marioni RE, Gustafsson S, Joehanes R, Irvin MR, et al.
Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies.Circulation. Cardiovascular genetics
1/2017
10
1

Hibar DP, Adams HH, Jahanshad N, Chauhan G, Stein JL, Hofer E, et al.
Novel genetic loci associated with hippocampal volume.Nature communications
1/2017
8

13624
Josse RG, Majumdar SR, Zheng Y, Adler A, Bethel MA, Buse JB, et al.
Sitagliptin and risk of fractures in type 2 diabetes: Results from the TECOS trial.Diabetes, obesity & metabolism
1/2017
19
1
78-86
Jutten RJ, Harrison J, Jan de Jong F, Aleman A, Ritchie CW, Scheltens P, Sikkes SAM
A composite measure of cognitive and functional progression in Alzheimer's disease: Design of the Capturing Changes in Cognition studyAlzheimer's & Dementia: Translational Research & Clinical Interventions
1/2017
3
1
130-138
Luciano M, Corley J, Cox SR, Valdés Hernández MC, Craig LC, Dickie DA, et al.
Mediterranean-type diet and brain structural change from 73 to 76 years in a Scottish cohort.Neurology
1/2017
88
5
449-455
Marshall CR, Howrigan DP, Merico D, Thiruvahindrapuram B, Wu W, Greer DS, et al.
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.Nature genetics
1/2017
49
1
27-35
Mendelson MM, Marioni RE, Joehanes R, Liu C, Hedman ÅK, Aslibekyan S, et al.
Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach.PLoS medicine
1/2017
14
1
e1002215
Mina TH, Lahti M, Drake AJ, Räikkönen K, Minnis H, Denison FC, et al.
Prenatal exposure to very severe maternal obesity is associated with adverse neuropsychiatric outcomes in children.Psychological medicine
1/2017
47
2
353-362
Neoptolemos JP, Palmer DH, Ghaneh P, Psarelli EE, Valle JW, Halloran CM, et al.
Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial.Lancet (London, England)
1/2017



Pinter D, Ritchie SJ, Doubal F, Gattringer T, Morris Z, Bastin ME, et al.
Impact of small vessel disease in the brain on gait and balance.Scientific reports
1/2017
7

41637
Springelkamp H, Iglesias AI, Mishra A, Höhn R, Wojciechowski R, Khawaja AP, et al.
New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.Human molecular genetics
1/2017



Thompson PM, Andreassen OA, Arias-Vasquez A, Bearden CE, Boedhoe PS, Brouwer RM, et al.
ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide.NeuroImage
1/2017
145
Pt B
389-408
Valdés Hernández MD, Qiu X, Wang X, Wiseman S, Sakka E, Maconick LC, et al.
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Cornel JH, Bakris GL, Stevens SR, Alvarsson M, Bax WA, Chuang LM, et al.
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Gibb FW, Stewart A, Walker BR, Strachan MW
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Mercaptopurine versus placebo to prevent recurrence of Crohn’s disease after surgical resection (TOPPIC): a multicentre, double-blind, randomised controlled trialLancet Gastroenterology and Hepatology
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Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.Circulation. Cardiovascular genetics
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Effects of environmental risks and polygenic loading for schizophrenia on cortical thickness.Schizophrenia research
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O’May F, Gill J, Black H, Rees C and Chick J
An exploration of the lived experiences of people with alcohol-related harm in ScotlandJournal of Substance Use
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Metformin in adults with type 1 diabetes: design and methods of REducing with MetfOrmin Vascular Adverse Lesions (REMOVAL): an international multicentre trial.Diabetes, obesity & metabolism
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Ritchie SJ, Tucker-Drob EM, Starr JM, Deary IJ
Do Cognitive and Physical Functions Age in Concert from Age 70 to 76? Evidence from the Lothian Birth Cohort 1936.The Spanish journal of psychology
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KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference.Proceedings of the National Academy of Sciences of the United States of America
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When do myopia genes have their effect? Comparison of genetic risks between children and adults.Genetic epidemiology
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Endothelial Function, Inflammation, Thrombosis, and Basal Ganglia Perivascular Spaces in Patients with Stroke.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
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Randomized double-blind clinical trial comparing basal insulin peglispro and insulin glargine, in combination with prandial insulin lispro, in patients with type 2 diabetes: IMAGINE 4.Diabetes, obesity & metabolism
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The α7 Nicotinic Agonist ABT-126 in the Treatment of Cognitive Impairment Associated with Schizophrenia in Nonsmokers: Results from a Randomized Controlled Phase 2b Study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
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Metformin Increases Cortisol Regeneration by 11βHSD1 in Obese Men With and Without Type 2 Diabetes Mellitus.The Journal of clinical endocrinology and metabolism
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Adapting to Aging: Older People Talk About Their Use of Selection, Optimization, and Compensation to Maximize Well-being in the Context of Physical DeclineJournal Of Gerontology: Social Sciences
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Epigenetic Signatures of Cigarette Smoking.Circulation. Cardiovascular genetics
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Efficacy and Safety of Liraglutide Added to Insulin Treatment in Type 1 Diabetes: The ADJUNCT ONE Treat-To-Target Randomized Trial.Diabetes care
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A Case-control Study in an Orcadian Population Investigating the Relationship between Human Plasma N-glycans and Metabolic SyndromeJournal of Glycomics & Lipidomics
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Optimization and Reproducibility of Aortic Valve 18F-Fluoride Positron Emission Tomography in Patients With Aortic Stenosis.Circulation. Cardiovascular imaging
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Personality Polygenes, Positive Affect, and Life Satisfaction.Twin research and human genetics : the official journal of the International Society for Twin Studies
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Multicentre, prospective, randomised, open-label, blinded end point trial of the efficacy of allopurinol therapy in improving cardiovascular outcomes in patients with ischaemic heart disease: protocol of the ALL-HEART studyBMJ Open
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Design of DEVOTE (Trial Comparing Cardiovascular Safety of Insulin Degludec vs Insulin Glargine in Patients With Type 2 Diabetes at High Risk of Cardiovascular Events) - DEVOTE 1.American heart journal
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Identification of polymorphic and off-target probe binding sites on the Illumina Infinium MethylationEPIC BeadChip.Genomics data
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Quantitative assessment of myocardial blood flow in coronary artery disease by cardiovascular magnetic resonance: comparison of Fermi and distributed parameter modeling against invasive methods.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
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Magnetic resonance elastography – towards a stiffness atlas of the canine brain for translational neurologyJournal of Veterinary Internal Medicine
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Increased levels of 3-hydroxykynurenine parallel disease severity in human acute pancreatitis.Scientific reports
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52 Genetic Loci Influencing Myocardial Mass.Journal of the American College of Cardiology
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Fatigue and cognitive function in systemic lupus erythematosus: associations with white matter microstructural damage. A diffusion tensor MRI study and meta-analysis.Lupus
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Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits.Nature genetics
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Strong cider sold in scotland appears to be almost exclusively for dependent drinkers.Clinical medicine (London, England)
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Does metformin reduce excess birthweight in offspring of obese pregnant women? A randomised controlled trial of efficacy, exploration of mechanisms and evaluation of other pregnancy complicationsEfficacy and Mechanism Evaluation
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Age-Dependent Pleiotropy Between General Cognitive Function and Major Psychiatric Disorders.Biological psychiatry
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Differential lower airway dendritic cell patterns may reveal distinct endotypes of RSV bronchiolitis.Thorax
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Genetic and Environmental Risk for Chronic Pain and the Contribution of Risk Variants for Major Depressive Disorder: A Family-Based Mixed-Model Analysis.PLoS medicine
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Feasibility, Accuracy, and Repeatability of Suprathreshold Saccadic Vector Optokinetic Perimetry.Translational vision science & technology
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ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: A rationale for safer glucocorticoid replacement therapy.Science translational medicine
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Copy number variation of scavenger-receptor cysteine-rich domains within DMBT1 and Crohn's disease.European journal of human genetics : EJHG
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A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.Nature communications
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Genome-wide association study of copy number variation with lung function identifies a novel signal of association near BANP for forced vital capacity.BMC genetics
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A century of trends in adult human height.eLife
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Alton EWFW, Armstrong DK, Ashby D, Bayfield KJ, Bilton D, Bloomfield EV, Boyd AC, Brand J, Buchan R, Calcedo R, Carvelli P, Chan M, Cheng SH, Collie DS, Cunningham S, Davidson HE, Davies G, Davies JC, Davies LA, Dewar MH, Doherty A, Donovan J, Dwyer NS, Elgmati HI, Featherstone RF, Gavino J, Gea-Sorli S, Geddes DM, Gibson JSR, Gill DR, Greening AP, Griesenbach U, Hansell DM, Harman K, Higgins TE, Hodges SL, Hyde SC, Hyndman L, Innes JA, Jacob J, Jones N, Keogh BF, Limberis MP, Lloyd-Evans P, Maclean AW, Manvell MC, McCormick D, McGovern M, McLachlan G, Meng C, Montero MA, Milligan H, Moyce LJ, Murray GD, Nicholson AG, Osadolor T, Parra-Leiton J, Porteous DJ, Pringle IA, Punch EK, Pytel KM, Quittner AL, Rivellini G, Saunders CJ, Scheule RK, Sheard S, Simmonds NJ, Smith K, Smith SN, Soussi N, Soussi S, Spearing EJ, Stevenson BJ, Sumner-Jones SG, Turkkila M, Ureta RP, Waller MD, Wasowicz MY, Wilson JM, Wolstenholme-Hogg P; on behalf of the UK Cystic Fibrosis Gene Therapy Consortium
A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosisNIHR Journals Library
7/2016



Ballerini L, Lovreglio R, Valdes Hernandez MC, Gonzalez-Castro V, Munoz Maniega S, Pellegrini E, Bastin ME, Deary IJ, Wardlaw JM
Application of the ordered logit model to optimising Frangi filter parameters for segmentation of perivascular spacesProcedia Computer Science
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Genomic analysis reveals depression due to both individual and maternal inbreeding in a free-living mammal population.Molecular ecology
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Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.American journal of human genetics
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Getting Spearman off the Skyhook: One More in a Century (Since Thomson, 1916) of Attempts to Vanquish g.Psychological inquiry
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Third European Stroke Science Workshop.Stroke
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CONCEPTT: Continuous Glucose Monitoring in Women with Type 1 Diabetes in Pregnancy Trial: A multi-center, multi-national, randomized controlled trial - Study protocol.BMC pregnancy and childbirth
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Heavy Drinkers’ Perspectives on Minimum Unit Pricing for Alcohol in ScotlandSAGE Open
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Qureshi NR, Shah A, Eaton RJ, Miles K, Gilbert FJ,
Dynamic contrast enhanced CT in nodule characterization: How we review and report.Cancer imaging : the official publication of the International Cancer Imaging Society
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Glucocorticoids Acutely Increase Brown Adipose Tissue Activity in Humans, Revealing Species-Specific Differences in UCP-1 Regulation.Cell metabolism
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Ferumoxytol-enhanced magnetic resonance imaging methodology and normal values at 1.5 and 3T.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
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Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.Nature genetics
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Andrews PJ, Sinclair HL, Rodriguez A, Harris BA, Battison CG, Rhodes JK, et al.
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Berge E, Cohen G, Lindley RI, Sandercock P, Wardlaw JM, Sandset EC, et al.
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A Multicenter Trial of Remote Ischemic Preconditioning for Heart Surgery.The New England journal of medicine
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Vascular and plaque imaging with ultrasmall superparamagnetic particles of iron oxide.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
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Dennis M, Sandercock P, Graham C and Forbes J on behalf of the CLOTS (Clots in Legs Or sTockings after Stroke) Trials Collaboration
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Hyrich KL, Baildam E, Pickford H, Chieng A, Davidson JE, Foster H, et al.
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Systemic Atherosclerotic Inflammation Following Acute Myocardial Infarction: Myocardial Infarction Begets Myocardial Infarction.Journal of the American Heart Association
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Does white matter structure or hippocampal volume mediate associations between cortisol and cognitive ageing?Psychoneuroendocrinology
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Convergence in insulin resistance between very severely obese and lean women at the end of pregnancy.Diabetologia
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Acetaminophen metabolism after liver resection: A prospective case-control study.Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
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From "aisle" to "labile": A hierarchical National Adult Reading Test scale revealed by Mokken scaling.Psychological assessment
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The FOCUS, AFFINITY and EFFECTS trials studying the effect(s) of fluoxetine in patients with a recent stroke: a study protocol for three multicentre randomised controlled trialsTrials


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Effects of a vitamin D and leucine-enriched whey protein nutritional supplement on measures of sarcopenia in older adults, the PROVIDE study: a randomized, double-blind, placebo-controlled trial.Journal of the American Medical Directors Association
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Carolan CM, Smith A, Forbat L
Conceptualising psychological distress in families in palliative care: Findings from a systematic review.Palliative medicine
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The impact of diabetes on cognitive decline: potential vascular, metabolic, and psychosocial risk factors.Alzheimer's research & therapy
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The total margin of exposure of ethanol and acetaldehyde for heavy drinkers consuming cider or vodka.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
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Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations.American journal of human genetics
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How Has the Age-Related Process of Overweight or Obesity Development Changed over Time? Co-ordinated Analyses of Individual Participant Data from Five United Kingdom Birth Cohorts.PLoS medicine
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