New! Bursaries for patient involvement
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March 2017

ACCORD has set up a bursary fund to support researchers to actively involve patients and the public in research in the University of Edinburgh and NHS Lothian.

The bursaries will support involvement that can’t otherwise be costed, for example prior to grant application. They will not normally fund PPI activities which can be costed into a grant application. Examples of activities which can be funded include:

  • setting up meetings with groups of patients, carers, service users or the public. For example hiring a venue external to your organisation, providing refreshments
  • reimbursement for patients for their time
  • reimbursement of out-of-pocket expenses incurred by members of the public such as travel, subsistence and carer costs
  • materials which would not normally be accessible within your organisation.

The maximum bursary is £500 and a total of £1,000 is available for this round.

Please download the full details and application forms for further information. For further information contact Allison.Worth@ed.ac.uk.


We got silver!
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January 2017

Both the labs and office areas of the Wellcome Trust CRF building were awarded silver in the 2016/17 Sustainability Awards! The CRF aims to work in the most sustainable way possible.

Further information about the awards can be found on the University of Edinburgh's Social Responsibility and Sustainability website.


We are hiring: CRF Deputy Director
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Vacancies

January 2017

We are hiring a new CRF Deputy Director. This is an exciting opportunity for an innovative and proactive individual to lead our dynamic multidisciplinary team.

For more information and the full job advert, please go to our Vacancies page.


New 3T Siemens Prisma MRI for the BRIC

December 2016

BRIC2-tractography

We are delighted to announce that the 3T Siemens Prisma MRI (neuro-optimised) scanner is now live, located at the RIE.

The image above is the first tractography image reconstructed from diffusion tensor imaging, and showing nerve connections between different parts of the brain, combined with high definition structural images showing the hippocampus (red objects) where memories are formed and stored.

Our BRIC team are excited about the future research projects, where the Edinburgh Imaging facility (RIE) will be providing imaging of the brain across the life course, for example neonatal research, cognitive ageing and dementia research. It will be an excellent addition to the current 1.5T MRI scanner located at the WGH, and allow our team to further develop advanced imaging techniques


Clinical research in the Festival City
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November 2016

"Based in Edinburgh’s royal hospital for sick children, Dr Thom O’Neill is a paediatric clinical research fellow."

The video is showing Dr Thom O’Neill seeing a patient in the Edinburgh CRF's paediatric unit while talking about his career.

Read more in the article by the Guardian titled "What’s it like being a junior doctor in Scotland?"


We are going for silver!
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Sustainability Awards

August 2016

The Wellcome Trust CRF building was awarded a bronze sustainability award in 2015 for offices and labs. This year we are going for silver! The CRF aims to work in the most sustainable way possible.

Further information about the awards can be found on the University of Edinburgh's Social Responsibility and Sustainability website.


Edinburgh CRF Staff News

July 2016

Goodbye

Elspeth Currie, who has been with the CRF for over 5 years retires in July this year. We are very sorry to see Elspeth leave, she will be missed, but we wish her much happiness in her retirement and future ventures and thank her for her many years of hard work!

Hello

We are delighted to welcome on board Marie Leslie as our new Administration Manager. Marie joins us with a wealth of experience and at an exciting time for the CRF, as we expand our Operational Management Team and facilitate the opening of the new Centre for Dementia Prevention.


Professor Steve Cunningham appointed as Children’s CRF Director and CRF Associate Director
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Steve Cunningham

July 2016

Edinburgh Clinical Research Facility is delighted to announce the appointment of Professor Steve Cunningham as Children’s CRF Director and CRF Associate Director. Steve is Consultant and Honorary Professor in Paediatric Respiratory Medicine at the Royal Hospital for Sick Children/Department of Child Life and Health.

“It is a terrific honour to be appointed as the Director of the Children's Clinical Research Facility and Associate Director of Edinburgh CRF. Embedding research in clinical practice is vital – and the CRF facilities in Edinburgh help make that happen, not just for our large international projects, but as pilot studies to build clinical trials for the future. We will move in 2017 to a new expanded facility in Edinburgh Children's Hospital at Little France and with that develop future world leading research opportunities for children.“


Edinburgh CRF Brochure 2016
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June 2016

Our new brochure is out summarising another successful year for Edinburgh CRF.

"Supporting clinical research over three hospital sites and across many clinical specialities represents a challenge to our dedicated and committed staff. Edinburgh CRF now employs over 100 staff across our clinical and core services. Using a mixed model of NHS Research Scotland (NRS) funded posts and CRF income streams, we contribute to the delivery of our local and national research agenda."


Professor Craig Ritchie appointed as Associate Director
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Craig Ritchie

May 2016

Edinburgh Clinical Research Facility is delighted to announce the appointment of Professor Craig Ritchie as Associate Director. Craig is Professor of the Psychiatry of Ageing and is co-Director of the Centre for Dementia Prevention (CDP). The appointment is in recognition of the commitment to collaboration between Edinburgh CRF and the CDP in the rapidly developing area of dementia research.

“I am honoured to be appointed as Associate Director of the Edinburgh CRF. As the lead for studies such as EPAD and PREVENT, the appointment reflects the ongoing commitment in Edinburgh to dementia research and strengthens our capacity for translational medicine in the neurosciences. We are privileged in Edinburgh to have access to world-leading facilities at the CRF to support quality biomedical research across a vast array of clinical areas.”


SAVE THE DATE! Edinburgh Clinical Trials Management Course 2016!

Thursday 1st and Friday 2nd December 2016

The 2 day Edinburgh Clinical Trials Management Course (ECTMC) will take place on:

Date: Thursday 1st and Friday 2nd December 2016
Time: 09:00 – 17:00
Location: John McIntyre Conference Centre, Pollock Halls, 18 Holyrood Park Rd, Edinburgh EH16 5AY

Further information will be available soon.


Scottish Metabolomics Network Inaugural Meeting 2015
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November 2015

The Scottish Metabolomics Network was launched following an initiative by SULSA to encourage integration of the Scottish Metabolomics facilities.

The Network will be holding its first meeting on the 30th November and 1st December in Edinburgh organised by Dr Ruth Andrew and Dr Andy Finch.

For further information view our Mass Spectrometry's Scottish Metabolomics Network Inaugural Meeting 2015 webpage.


Another high profile paper for NHS Lothian and University of Edinburgh
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October 2015

"In Europe, traumatic brain injury is the most common cause of permanent disability in people younger than 40 years of age, with the annual cost exceeding €33 billion (approximately $37.5 billion in U.S. dollars). Recent statistics show a 21% increase in the incidence of traumatic brain injury during the past 5 years — three times greater than the increase in population. Despite this, management of traumatic brain injury has been underrepresented in medical research as compared with other health problems. [...] Hypothermia is one treatment option for this patient group." (Andrews PJ, Sinclair HL, Rodriguez A et al., 'Hypothermia for Intracranial Hypertension after Traumatic Brain Injury')

Edinburgh CRF’s Western General site supported this trial that led to the publication 'Hypothermia for Intracranial Hypertension after Traumatic Brain Injury' in the The New England Journal of Medicine.

You can access this publication on our Publications page.


Remote Ischemic Preconditioning and Outcomes of Cardiac Surgery
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October 2015

Edinburgh CRF’s Royal Infirmary site supported this multicentre clinical trial funded by the NIHR and MRC Efficacy and Mechanism Evaluation (EME) Programme and the British Heart Foundation. Read more in the article published in the New England Journal of Medicine in October 2015.

You can access this publication on our Publications page or download the full paper.


Edinburgh CRF supports high quality research
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September/October 2015

Our Children’s CRF paediatric team supported the 'Oxygen saturation targets in infants with bronchiolitis (BIDS): a double-blind, randomised, equivalence trial' - a study in infants with bronchiolitis.

Funded by the National Institute for Health Research, Health Technology Assessment programme, this study aimed to assess whether outcomes in infants managed to a target oxygen saturation level of 90% varied from those managed to a target 94% O2 saturation. Prof Steven Cunningham and his team demonstrated equivalence between the two targets in terms of adverse events, readmissions to hospital and transfer to high dependency. The study was published in The Lancet in September 2015.

You can access this publication on our Publications page.


Disconnected Mind Newsletter
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September 2015

LBC1936 Study Update – Wave 4

Our Nursing and Clinical team at the Wellcome Trust Clinical Research Facility has "now seen 253 participants [...], completing cognitive and physical tests for a fourth time, at about age 79."

"So far, 153 have already completed a brain MRI scan, 212 have completed a Doppler ultrasound of their carotid arteries, and 196 have worn and returned the activPAL activity monitor."

Download the Disconnected Mind Newsletter for further information.


Edinburgh CRF Brochure 2015
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September 2015

Our new brochure is out summarising another successful year for Edinburgh CRF.

Clinical Research Facilities across the UK are now widely accepted as valuable infrastructure for the delivery of quality, safety and efficiency in clinical research. Close collaboration between NHS Lothian and the University of Edinburgh is fundamental to Edinburgh CRF’s delivery of clinical research across three hospital sites in Lothian.


Ruth Andrew appointed Chair of Pharmaceutical Endocrinology

August 2015

Mass Spectrometry Core Director Ruth Andrew was appointed Chair of Pharmaceutical Endocrinology on August 1st 2015. Congratulations Professor Andrew!


Edinburgh CRF Staff News

August 2015

Hello

Chelsea Todd will start a 9 month modern apprenticeship with the admin team on 3rd August. We are looking forward to having a new member of the team and hope she will gain a lot from her time with us.

Goodbye

Marianne Rudden, who has been with the CRF for over 12 years, is retiring in August. We are very sorry to see her go and she will be badly missed, but we wish her much happiness in her retirement.


MHRA Phase I Accreditation Status Renewed
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July 2015

Re- accreditation of our adult facilities at the WTCRF and RIECRFD and first accreditation of the Children’s CRF in July 2015.

We also recently appointed a dedicated CRF Lead Nurse for Phase I/Education - Fiona Mitchell.

The adult clinical facilities at the WTCRF and RIECRF have been accredited under the MHRA Phase I Accreditation Scheme since July 2011. To read more about our Phase I Accreditation visit our page on Phase I Studies.


Science Insights Work Experience Programme at Edinburgh CRF
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July 2015

The Edinburgh CRF Genetics core hosted school students from the Science Insights programme in late July.

"Up to 20 high school students spend a week following a varied programme of activities on three different University of Edinburgh campuses, designed to give a real insight into research and work in biological sciences." Read more about the programme


CRF Nursing and Clinical Open-Afternoon Sessions a Success
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Curious about a career in Clinical Research

June/July 2015

The adult CRF Nursing and Clinical facilities opened their doors at the WTCRF and RIECRF for two afternoons in June and July 2015 to encourage nurses and learner nurses (pre and post registered) to visit the CRF and consider a nursing career in Clinical Research. This was highly successful with nurses from all specialties attending on both sites to raise awareness of the CRF and career options available.


Professor Stuart Forbes and Professor Brian Walker receive Awards

April 2015

Professor Stuart Forbes received a MRC Medical Research Council Award for £3.6 million to take forward his work on an autologous macrophage therapy for liver cirrhosis. This work will progress to include a First in Human(FIH) clinical trial which will be conducted in the Edinburgh CRFs Phase I Accredited RIECRF site.

Professor Brian Walker, University of Edinburgh also received a Wellcome Trust Senior Investigator Award in April 2015 to take forward his work on tissue-specific control of cortisol versus corticosterone in humans.


New Co-Director of the CRFs Genetics Core

November 2014

In November 2014 Professor Tim Aitman, Professor of Molecular Pathology and Genetics and the Director of Clinical Genomics in Edinburgh Genomics became a Co-Director of the CRFs Genetics Core. This will assist the CRF Genetics Core in working closely with, and complimenting the work of Edinburgh Genomics.


Prof. David Newby - Air Pollution and Heart Attacks
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October 2014

Professor David Newby, Director of the Edinburgh Clinical Research Facility, presents the second lecture in the 2014 Our Changing World series, entitled "Air Pollution and Heart Attacks".

Air pollution is one of the leading causes of heart attacks and death world-wide. This is principally caused by nano-particles generated by the combustion of fossil fuels and vehicle engine emissions.

Although the highest levels of air pollution are seen in developing countries, even modest levels of air pollution in Europe and North America can cause substantial adverse health effects.

The lecture will cover the size of the problem, explore the scientific evidence and highlight ways to reduce the risk.